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Jun. 29, 2018 - 3:52 - American Postal Workers Union President Mark Dimondstein on why he disagrees with President Trump’s plan to privatize the post office.

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What causes a baby to laugh in their sleep?

It’s not entirely clear what causes a baby to laugh in their sleep. We don’t know for sure whether babies dream, although they do experience an equivalent of REM sleep called active sleep.

Since it’s impossible to really know whether babies dream, it’s believed that when babies laugh in their sleep, it’s often a reflex rather than a response to a dream they’re having. For example, many researchers note that babies may twitch or smile in their sleep during active sleep.

When babies go through this type of sleep, their bodies can make involuntary movements. These involuntary movements might contribute to smiles and laughter from babies during this time.

In very rare instances, there are types of seizures that can occur in infants that cause episodes of uncontrolled giggling, called gelastic seizures. These are short seizures, lasting around Marco Dal Maso Mens Ara DoubleRectangle Ring w/ Diamonds Size 10 P3a6PNj3ha
, which can start in infancy around 10 months old . They can occur as the baby is falling asleep, or while they’re asleep it might wake them up.

If you notice this happening regularly, multiple times a day, and accompanied by a vacant stare, or if it happens with grunting or unusual bodily movements or squirming, talk to your pediatrician.

Diagnosing this condition can be tricky, and the doctor will want to know more about the situation and possibly run some diagnostic tests to be sure of what’s going on.

The bottom line

While there are instances where laughing in your sleep can indicate something serious, in general, it’s a harmless occurrence and you have nothing to worry about.

For babies and young children, laughing in their sleep is typical and generally not a cause for concern. This is especially true if it’s not accompanied by any abnormal behavior.

If you’re experiencing sleep disturbances or issues with sleeping, it’s worth talking with your doctor about your concerns. They may refer you to a sleep specialist for further evaluation.


Herbal teas are popular beverages when it comes time to relax and unwind. Here are the 6 best teas that help you sleep.


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Ambien helps millions achieve better sleep, but many have experienced strange and dangerous side effects. Here are some of them.

Federal Baseball a Washington Nationals community
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Tanner Roark was better this time around against the Nationals’ NL East rivals, but the Phillies took the series opener in Citizens Bank Park, 4-3.

By Patrick Reddington @federalbaseball
Share Nationals drop third straight, 4-3 Phillies in series opener in Citizens Bank Park...
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Philadelphia Phillies’ right-hander Aaron Nola dominated the Washington Nationals over 7 2 3 innings tonight in Citizens Bank Park, giving up five hits and one earned run in what ended up a 4-3 win, which extended the starter’s personal unbeaten streak to seven straight starts.

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’s adjustments: Tanner Roark couldn’t get through the fifth last time out against the Phillies during the series in D.C., and he spent the rest of that game watching film to try to identify a mechanical issue that might be behind his struggles.

’s adjustments:

He thought he found a little something.

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said, “... and then you just keep thinking about it and how to change it and it just keeps growing and growing when it’s just something small.”

Tanner Roark's really got some top-notch facial hair going on.

Roark gave up seven hits, four walks, and six earned runs in that outing, after giving up six hits, three walks, and three earned runs in 6 1 3 IP against the Phillies when he faced them back on May 5th.

Wednesday, July 4th, 2018
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/ IRREPLACEABLE YOU: A Forgettable Moment Of Catharsis

IRREPLACEABLE YOU: A Forgettable Moment Of Catharsis

While cathartic in the emotional expression of the finality of death, Irreplaceable You fails to be memorable, forgotten long after the credits have rolled.

June 1, 2018
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“The trouble is, you think you have the time” – Buddha

This one sentence could not be more inspirational, or true. When we find something deep and meaningful, we never want to let it go, thinking the time we will have is never ceasing. Until it is.

When time is running out, there is no more control on your life, or the lives of others. You have only the constant metronome keeping the beat to the inevitable end. There is nothing you can do but drown in an overwhelming flood of emotions or enjoy the remaining time you have left as you prepare for the ultimate closure. This is the focus of Netflix’s latest film Irreplaceable You from director Stephanie Laing .

Stephanie Laing

Not everyone accepts the knowledge of knowing they are going to die the same way.Some may never move on, stuck in a stage of grief, while others have reached the acceptance of their life, maintaining a solemn understanding of the freedom their knowledge and limitation gives them. Still, others struggle against the control they have lost on their life and others, fighting during their last moments to meticulously and obsessively plan for when they will no longer be around.

source: Netflix

True soulmates, destiny, until death do we part – words and phrases typically associated with the ultimate love story. Two people destined to be together for all eternity, overcoming any obstacle that is thrown their way. For Abbie ( Gugu Mbatha-Raw ) and Sam ( Michiel Huisman ), their love story, built since childhood, does not conform to this formula. Engaged to be married, with thoughts of a family and a life time together on the mind, Abbie’s world implodes in front of her as she is given a diagnosis of terminal cancer.

Gugu Mbatha-Raw Michiel Huisman

Facing the end of her life and the end of a love story, Abbie is faced with the realization that Sam is also facing a final moment in his life – the end of a forever they were suppose to have. Realizing everything Sam will now have to face on his own, her sadness turns to fear as the image of Sam grieving and alone permanently becomes ingrained in her mind.

From this moment on, Abbie is determined to find Sam the perfect replacement – a new Abbie. Someone who can find his glasses when he has lost them, cook chicken and do his laundry. Yet, as Abbie struggles to control the outcome of Sam’s life after she is gone, she finds that her final moments may not always be what she planned.

The impact factors of other journals also increased:

The Editor-in-chief of IUCr Journals, Professor Samar Hasnain commented:" Each of our journals have made a significant improvement in the latest impact factor results. We thank our authors, reviewers, editors and co-editors for their commitment to ensuring that the best of structural science and underpinning technology and methods is reported in IUCr Journals. This is the first time that four of our journals concurrently have an impact factor above 6, and we look forward to building on this success ."Peter Strickland, Executive Managing Editor of IUCr Journals, noted:" This is first time, since I started working for the IUCr some 30 years ago, that I can remember all of the journals increasing their impact factors in the same year. "

For more details, see

Ptychographic X-ray imaging is used to characterize the structure and properties of matter and materials. While the method has been around for 50 years or so, wide use was at first hampered by the experimental process being slow and the computational processing of the data to produce a reconstructed image being expensive. But in recent years, advances in detectors and X-ray microscopes at light sources such as Lawrence Berkeley National Laboratory's Advanced Light Source have made it possible to measure a ptychographic data set in seconds. As a result, today ptychography is used in a range of scientific domains, including condensed-matter physics, cell biology and electronics.

Reconstructing ptychographic data sets can be a data-intensive challenge, as it involves solving a difficult phase-retrieval problem, calibrating optical elements and dealing with experimental outliers and 'noise'. To address this challenge, Berkeley Lab scientists developed (scalable heterogeneous adaptive real-time ptychography), which enables the reconstruction of millions of phases of ptychographic image data per second. Since being introduced in 2016, has had notable successes in the analysis of magnetic thin films, magnetozomes and three-dimensional battery materials.

Now members of the collaboration have developed a model that further enhances 's reconstruction capabilities. The new algorithm, (gradient decomposition of the probe/alternating direction method of multipliers), is described in a recent article in Section A [ Chang (2018) A 74 , 157-169 ] and was featured on the cover of the May issue. takes advantage of state-of-the-art mathematical aspects of phase retrieval, background-noise optimization and detector 'denoising', allowing to handle more light than before, enabling faster data acquisition and higher time resolution, and ultimately more scientific discoveries.

'The goal was to offer the ability to quickly discover interesting nanoparticles at full resolution by enabling rapid feedback from the microscopists at the beamlines,' said Stefano Marchesini, a staff scientist at Berkeley Lab and a co-author of the article. 'Even when the next-generation coherent light sources come online, we may be able to extend the X-ray energies that can be used in ptychography by using this model.'

The results from structure prediction programs have demonstrated that any organic molecule has the potential to interrelate with its siblings in a number of different ways, the observed crystal structure representing an energy minimum where the contributions from various types of intermolecular interactions have been carefully balanced. Systematic investigations of molecules that share one important moiety/feature provide valuable experimental data for the understanding of this balance and for rationalizing important trends, even among other sets of compounds. Amino acids constitute an attractive group for such a survey, with a common polar head and a variable side chain. Crystal structures of more than 120 regular, acyclic amino acids have been published in the past, meaning that the 20 proteinogenic amino acids represent but a minor fraction of the experimental material. If these amino acids are used, however, to construct dipeptides, they alone leave 20 x 20 = 400 different options. As of June 2018, crystal structures are only available for 104 of them.

is a subgroup of particular interest. These are based on combinations of the five non-polar amino acids alanine (Ala), valine (Val), isoleucine (Ile), leucine (Leu) and phenylalanine (Phe) only, meaning that hydrogen bonds are essentially limited to connecting the constant parts of the molecules, the peptide main chains. Accordingly, any change in crystal structure upon amino acid substitution is due to the side chain.

The crystal structure of Val-Leu acetonitrile solvate presented in Görbitz (2018). B 74 , 311-318 is the 25th and last missing piece in the 5 x 5 puzzle of hydrophobic dipeptide structures. This “completion event” is used here as an opportunity to review their crystal packing arrangements and hydrogen-bonding pattern preferences, the associated peptide conformations and the sometimes unexpected impact a seemingly modest amino acid substitution can have not only on the crystal structure but also on the propensity to include co-crystallized solvent molecules.

IUCrJ Editorial Board Member Richard Henderson (MRC LMB, Cambridge, UK) has been made a Companion of Honour in Queen Elizabeth II's 2018 Birthday Honours list for services to electron microscopy of biological molecules. The order is a special award held by only 65 people at any one time.


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